Kirinmaru arrives and intervenes in the battle by scattering the Rainbow Pearls. Zero, enraged with her brother, cuts ties with him and flees. Sesshomaru chases after her, leaving Towa, Setsuna, and Moroha to face off against Kirinmaru.

Towa and Setsuna hire Moroha to assist them with slaying Zero. They go to the location where the Great Dog Demon had perished long ago and find Zero, but Riku is there to defend her.

Zero appears before the girls and removes the seal suppressing Setsuna's demon powers. When Setsuna transforms and loses control, Towa and Moroha struggle to stop her rampage.

On the night of the new moon, Towa is visited by Riku and he reveals his intentions of gathering all seven of the Rainbows Pearls. During their conversation, Totetsu suddenly appears to attack the currently powerless Towa.

While on the lookout for demons deep in the mountains, Setsuna reveals to Towa what occurred during the 10 years they were separated.

The demon slayers are offered a chance to be employed by the deputy shogun, but they must battle against a group of bounty hunters, which includes Moroha. Not wanting Towa to get involved, the two parties try to keep the battle a secret.

Towa and Setsuna break free from Konton's trap and defeat him. They meet up with Moroha to finish off Totetsu, but he flees the battle. The girls chase after him but are suddenly attacked and find themselves face to face with Kirinmaru.

Riku informs Towa, Setsuna, and Moroha about the whereabouts of Totetsu and they set out to slay him. In their pursuit, Totetsu leads them to a ravine where, unbeknownst to the girls, Konton has set up a trap to ensnare and destroy them.

Konton barters with Yawaragi, Moroha's former master, to take Moroha's life in exchange for an item she seeks. Yawaragi appears before Moroha, and a showdown between master and pupil begins.

Riku recalls events that took place beginning 18 years ago, when Inuyasha receives a new Black Pearl. 4 years later, on the night of Towa and Setsuna's birth, Inuyasha and Sesshomaru learn of a cataclysmic event that needs to be stopped.

Towa and Setsuna set off to slay Homura, an evil mountain god who has abducted a beautiful maiden named Tamano. However, Homura is shocked at the sight of the twins; it turns out that he was involved in the forest fire that separated them ten years ago.

Tōtetsu, the final member of the Four Perils, has been wrecking havoc by devouring high-level Shinto monks and priests to attain their increasingly powerful spiritual abilities. One of his targets is none other than Miroku, Hisui's father! Can the Half-Demon Princesses and demon-slayers reach him in time before Tōtetsu devours him?

Nikosen was a sage before evil consumed his soul and transformed him into a demon. Konton orders him to kill the Half-Demon Princesses. Nikosen's ambush catches Towa at a bad time, when her demon powers are fading and she is slowing turning into a human.

Something wicked lurks in the Man-Eating Pond, devouring any human, beast or bird that comes near. On their way to slay the creature, Towa and Setsuna meet Hikomaru and Chiyo, siblings who lost their parents to the pond.

The Half-Demon Princesses are tasked with slaying Kinka and Ginka, conjoined twins of the Ka Demon Tribe whose battles for dominance have been wreaking havoc everywhere.

Moroha accepts a job to slay Konton, a member of the Four Perils said to have defeated Meioju, a demon beast with the ultimate armored shell.

The owl demon Yotsume flees the deputy shogun's estate to the lair of Kyuki, a member of the Four Perils. Kyuki lends Yotsume a Rainbow Pearl to help him unleash his Dream Gazing spell upon the Half-Demon Princesses, who are hot on his trail.

On her way to search for the Dream Butterfly, Towa meets a strange young man named Riku. Towa offers him an apple, and in thanks, Riku presents her with the genuine Kikujumonji sword.

Travelers are going missing one after another. Towa, Setsuna, and Moroha head to the northern mountains to crack the case, but instead they find a village completely overrun by ghost cats!

Safely back in the feudal era, Moroha heads to the corpse dealer to claim her bounty. Meanwhile, Towa and Setsuna take on a request to slay Jakotsumaru, a boy who has been extracting bones from humans and beasts in order to revive his father, the demon beast Tokotsu.

Towa decides to return to the feudal era to help Setsuna regain her memories. The trio enter the corridor leading to the feudal era, but within it awaits the spirit of a certain priestess.

In the present day, a demon emerges through the Sacred Tree at Higurashi Shrine with Setsuna, Towa's twin, and the bounty hunter Moroha in tow. Towa, Setsuna, and Moroha struggle to battle the demon, whose powers have been strengthened with two Rainbow Pearls, but seeing Setsuna in trouble awakens Towa's latent demon powers.

Half-demon twins Towa and Setsuna are separated from each other when a mysterious tunnel sends Towa into the future, where she is found and raised by Kagome Higurashi's brother Sota.

Towa Higurashi learns about an incident that took place decades ago involving a half demon named Inuyasha and a priestess named Kagome.