Silvia's case closely involves Enrico too, as some of his past finally emerges. While Caruso's tests show more and more the actual intent of putting Doc in trouble, Cecilia starts finding out the team's secrets.

In order to cure an imprisoned mother who allegedly attempted to kill her own daughter, Doc must fight the prejudice of the entire hospital, in the exact same moment he becomes the main target of the investigation. Doc and Agnese are suddenly brought closer by this new situation, but in the meanwhile Damiano has found out a compromising proof on Doc and the team, and now he must choose which side he's on.