An exciting evening at the Grand Old Opry in Nashville proves to be almost too exciting when a mysterious phantom appears. It's a "haunting" experience for the members of Mystery, Inc. when they must search for their missing friend, country singer Jerry Reed.

When Scooby-Doo and the kids travel to a small New England town to visit Shaggy's Uncle Nathaniel, they plunge into a maelstrom of mystery, encounter the ghost of Paul Revere and confront a spooky sea serpent with the aid of The Harlem Globetrotters!