After a wraith kills a psychic, Missouri investigates the death of her friend and calls in Dean and Jody. They help track down Missouri's granddaughter, who also has "the gift" and is the wraith's next target. Meanwhile, Sam tries to help Jack develop his powers.

Sam suggests that he and Dean work the case of a missing boy by themselves. Dean soon realizes that Sam is deliberately trying to be kind to him, while the Winchesters work a case of a deadly ghost and a house full of trapped spirits.