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With Colonel Glenn Talbot now on their trail, Coulson and his team seek refuge in the last place anyone would look, where they begin to uncover S.H.I.E.L.D.'s most dangerous secrets -- secrets that could destroy them all.
Coulson and his team find themselves without anyone they can trust, only to discover that they are trapped with a traitor in their midst.
With their world turned upside down, Coulson races to save the life of his one true love as the mystery of "The Cellist," which began in Marvel's The Avengers.
Set after the events of the Battle of New York, S.H.I.E.L.D. Agent Phil Coulson assembles his own team of skilled agents and operatives including Melinda May, Grant Ward, Leo Fitz, Jemma Simmons, and newly-recruited Skye investigate several dangerous cases including the Project Centipede and its leader, The Clairvoyant, while Coulson also searches for answers surrounding his mysterious resurrection.