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Sheldon goes to Vegas to win money for science. Also, Penny and Bernadette take Amy wedding dress shopping, but her terrible choice entangles them in a web of lies.
Sheldon's comic book store experiences changes when writer Neil Gaiman puts Stuart's store on the map. Also, Koothrappali takes credit for Penny's astronomical discovery, and friendships are threatened.
When Sheldon learns that his mother won't attend his wedding unless he invites his brother, Georgie, he and Leonard travel to Texas to end a family feud. Also, the Wolowitz kids inadvertently infest Amy, Bernadette, Wolowitz and Koothrappali with pinkeye.