When Sheldon kicks Amy out to work solo, she and Leonard bond during a series of science experiments. Also, Bert the geologist replaces Wolowitz in the band Footprints on the Moon, and Sheldon finds Penny a surprising source of scientific inspiration.

When Sheldon petitions Wil Wheaton to appear on the new Professor Proton show, Wil offers a role to Amy instead. Also, Penny gets angry when she thinks the female protagonist in Leonard's novel is based on her.