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Sheldon and Leonard get invited to a party at Wil Wheaton's house, and Howard gets an out-of-this-world opportunity.
Raj finally meets a girl he can communicate with.
Sheldon competes with the gang for his mother's attention when she comes to visit.
Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".