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Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".
When Howard and Bernadette decide they want to be married before his NASA launch, the gang rushes to put on a wedding.
NASA reschedules Howard's mission, putting his and Bernadette's wedding plans in jeopardy. Meanwhile, Leonard says something surprising to Penny in the bedroom.
Bernadette reconsiders marrying Howard after learning about his sexual history.
When Wolowitz gets to work with Stephen Hawking, Sheldon is willing to do anything to meet his hero.
Penny buys Leonard and Sheldon "Star Trek" collectibles as a thank-you, leading Sheldon to be haunted by Mr. Spock. Meanwhile, Raj decides he has met the "Future Mrs. Koothrappali" after his parents set him up on a date.
Sheldon chooses to play video games with the guys rather than go with Amy to her aunt's birthday party.
Sheldon's life is turned upside-down after his barber gets sick. Meanwhile, astronaut training causes Wolowitz to rethink his decision to go into space.
When an office at the University opens up, Sheldon must compete for it with his archenemy, Kripke. Meanwhile, a gift from Amy makes Penny uncomfortable.
When Sheldon is forced to take his vacation, he goes to work with Amy in her neurobiology lab. Meanwhile, Bernadette wants Howard to sign a pre-nup.
Sheldon's selfish demands force Leonard to reconsider their friendship. Meanwhile, Wolowitz tries to pick his astronaut nickname.
Leonard and Penny experiment with dating, while Raj develops a peculiar relationship with his phone's virtual assistant.
Everything might change when Leonard offers Penny a spur of the moment invitation to a romantic dinner for two.
Sheldon gets in trouble with Amy when he isn't impressed by her recent accomplishment, and Howard must come to grips with Bernadette's dislike of children.
Leonard must face his fears after being contacted by his high school tormentor.
Sheldon considers taking his relationship with Amy to the next level when Stuart from the comic book store asks her out on a date.
Leonard and Penny try hanging out alone, and Sheldon must overcome his fear of birds.
Amy is crushed when Bernadette and Penny go shopping for wedding dresses without her.
Cute comic book artist puts Leonard and Priya's relationship to the test, while Sheldon tries to scare the guys for Halloween.
Sheldon competes with the gang for his mother's attention when she comes to visit.
Sheldon and Leonard get invited to a party at Wil Wheaton's house, and Howard gets an out-of-this-world opportunity.
Raj finally meets a girl he can communicate with.
Leonard and Amy get to know each other better, while Howard and Bernadette spend the weekend with Mrs. Wolowitz.
Fight between Sheldon and Penny leaves Amy caught in the middle, while Leonard tries to spice up his long-distance relationship with Priya.
Penny worries that she's screwed things up permanently with her friends, while Sheldon takes command of the paintball team.
Sheldon and Amy's relationship takes a step forward, Penny makes big decisions in her professional and person life, Raj tries to prosper in the dating world with his newfound ability to talk to women, and Howard treats Bernadette to a very special surprise for the anniversary of their first date.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.
Penny regrets her sleeping with Raj and has become very good friends with Leonard, Leonard breaks up with Priya, Amy pushes Sheldon in their relationship eventually becoming boyfriend and girlfriend, Penny and the other women become a clique of their own, Howard prepares for his wedding and going into space to the International Space Station and Leonard asks Penny out as they begin "Leonard and Penny 2.0".
Sheldon begins a platonic relationship with Amy, Howard reconnects with Bernadette eventually asking her to marry him, Leonard begins to date Raj's sister Priya, Penny becomes friends with Amy and expresses regret at breaking up with Leonard.
Penny throws herself at Leonard after he returns from three months at the North Pole and they begin a relationship, Penny and Sheldon start a quirky friendship though she can still annoy him, Howard begins to date Bernadette Rostenkowski and Sheldon meets Amy Farrah Fowler.
Leonard and Penny's relationship takes a turn for the worse when they break up, but is quickly resolved. Soon their relationship progresses into a stronger friendship than before, while Sheldon and Penny's friendship slowly begins.
The lives of physicists Dr. Leonard Hofstadter and Dr. Sheldon Cooper are shaken up when an attractive young aspiring actress from Omaha, Nebraska named Penny moves into the apartment across the hall from theirs. Leonard begins to become hopelessly enamored of Penny, while she feels only platonic affection for him; as a result, she finds herself putting up with his closest and ever-present friends: his roommate, Sheldon, who appears borderline obsessive-compulsive; engineering whiz Howard Wolowitz, a desperately sex-crazed mama's boy who thinks that his 1960s-style clothing and hairstyle give him an air of cool hipness; and Dr. Rajesh "Raj" Koothrappali, who will not speak to her as he is too shy to talk to women (a case of selective mutism), unless intoxicated in which case he becomes a smooth talking yet highly overly aggressive womanizing flirt.
