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Wolowitz struggles with moving out of his mother's house. Meanwhile, Sheldon is caught in the middle of an argument between Amy and Wil Wheaton.
Sheldon's relationship with Stephen Hawking is threatened over a game of "Words with Friends," and Penny secretly enrolls in a class at the local college.
Howard and Raj try to get to the bottom of why Sheldon disappears every afternoon at 2:45. Meanwhile, Leonard and Penny deal with jealousy in their relationship.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.