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Leonard, Sheldon and Raj fight for tenure at the University, and the competition heats up when the girls get involved.
Howard struggles with whether or not he should open a letter from his father, and Leonard and Penny throw a "grown-up" cocktail party at the apartment.
Sheldon feels lost after one of his favorite TV shows gets canceled too soon and Amy tries to help him get over his compulsive need for closure. Meanwhile, Raj discovers a secret about his new love interest, Lucy.
Howard return from space and adjust to normal, married life on earth. Sheldon and Amy's unique relationship continues to progress, though at a slower pace than Amy wants. Leonard and Penny's relationship is business as usual, with Leonard once again proposing to Penny. Meanwhile, Raj finally meets a girl and enters a (somewhat) stable relationship, the demise of which leads to unexpected progress for Raj.