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Cullen's position is threatened after Durant files an injunction against the Union Pacific. Meanwhile, Elam deals with a dangerous newcomer.
Cullen helps Elam track down a dangerous criminal. Meanwhile, chaos erupts in Hell on Wheels as the town prepares to move down the tracks.
A cholera epidemic in Hell on Wheels has Cullen seeking fresh water to help save his workers. Meanwhile, Durant faces political fallout.
Bohannon abandons seeking revenge for the deaths in his family in order to battle Durant for control of the Union Pacific Railroad. Eva gives birth to a baby that was sired during her marriage to Gregory Toole. Elam proposes marriage to her, even though her post-partum depression weighs heavily on her. The Swede takes up with a Mormon family on their way to Fort Smith and later reveals his true nature.