While Grissom and the rest of the CSIs are out investigating new cases, Hodges leads Archie, Henry, Mandy and Wendy to believe that Grissom wants them to secretly band together that evening in an attempt to solve the four miniature killer cases.

The CSIs discover that several suspects in a woman's murder are members of a bizarre UFO club who believe that shape-shifting reptile-like aliens have mated with humans for centuries as a means of conquering the human race.