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Tensions rise when Holmes and Watson are forced to partner with Gareth Lestrade, Sherlock's former Scotland Yard colleague, on a bombing investigation.
Holmes' latest investigation takes him inside a professional dance company when an up-and-coming ballerina is murdered. Meanwhile, Watson embarks on a solo enquiry to find a homeless veteran when his friend alleges he was abducted.
Holmes and Watson consult on a case in which a man suspected of murdering his wife years ago receives a ransom demand for her safe return. Meanwhile, Lestrade overstays his welcome at the brownstone and seems unwilling to leave.
In Season Two, the pair has made a name for themselves as a successful crime-solving duo that can crack the NYPD's most impossible cases. They'll return to solve mysteries from the past, get mixed up with the mob, and come face to face with their greatest adversaries.