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Virginia unearths Masters' troubled childhood during a secret rendezvous.
Masters begins a new job at Memorial Hospital - under Betty's terms - only to find his boss insisting he leave Virginia behind in favor of a handpicked secretary. Johnson, meanwhile, still alienated at Maternity, is torn between pressing Masters to rehire her and staying by DePaul's side as her condition worsens.
Johnson tries to cover when she and Masters are seen by Langham leaving a hotel together after an evening tryst. Later, Masters attempts to bring Johnson aboard as his assistant at his new post; and Betty tries to conceal her infertility from Gene, over Masters' objections.
Dr. William Masters and Virginia Johnson struggle to get their work back on track while taking their relationship to a much more intimate place; Libby flounders in a loveless marriage and turns to volunteering.