After two CSA agents assassinate their mentors but don't remember the crimes, master puzzle-solver Cathy Davis, a.k.a. Jane Doe, connects the incidents to a secret government experiment in mind control. Now, Cathy must quickly uncover who is behind this murderous mission -- before the next agent kills.

DNA evidence and camera footage places a corrupt CEO as the prime suspect in the murder of a company whistle-blower, but Jane Doe believes the real killer may be a twin sibling.