When Hope Zion Hospital's Chief of Surgery ends up in a coma, he finds himself wandering the halls in spirit form. Stuck between worlds, he watches as his fiancée and the staff of the hospital fight to keep patients – and hope – alive.

After Charlie's hand moved in the last episode, Alex has high hopes for his recovery, while she treats a patient who already has multiple surgeries under his belt. Meanwhile, Charlie coaches a young man killed in a roofing accident who has unfinished business with his severely injured brother.