A mother's death initially appears to be a suicide, but when investigators start to interview those closest to her, an evil plot emerges. Dennis Murphy reports

When two tragic deaths occur within one week of each other in a wealthy area in California, families begin to wonder what happened inside a beachfront mansion. Josh Mankiewicz reports.

The parents of missing South Carolina woman Heather Elvis, Debbi and Terry Elvis, open up to NBC News' Andrea Canning about the search for their daughter.

A young woman's murder remains unsolved until someone comes forward to reveal her own harrowing story. Keith Morrison reports.

The sister of a man who died after robbing a bank when a bomb that was placed around his neck detonated talks about the case.

Dennis Murphy takes a comprehensive look at the pizza bombing case, which Dateline has reported on for more than a decade, and the bizarre criminal activity surrounding the case.

A pilot flees after a deadly plane crash, and becomes a fugitive living a double life for decades. He tells his story for the first time to Keith Morrison.

When a beloved teacher and former beauty queen goes missing in Georgia, it triggers a decade-long investigation that makes national headlines. Andrea Canning reports

Andrea Canning reports on a young, beloved woman who is found dead near a soccer field in Indiana. Detectives try to piece together a puzzle that leads them to the most unexpected of suspects.

Keith Morrison reports on a notorious serial killer, nicknamed Hannibal, who murdered several people while working as a confidential informant for the FBI.

When a soldier who just returned from Afghanistan is gunned down on the side of the road in Kentucky; detectives quickly uncover a secret that could solve the case.

After being severely beaten in her own home, a high school girl goes under hypnosis to try to identify her attacker.

In-depth look at the growing homeless epidemic affecting half a million Americans, including an eye-opening tour of L.A.'s Skid Row, the nation's epicenter of homelessness. Craig Melvin reports.

A murder case considered closed by North Dakota detectives is suddenly reopened when a confidential informant comes forward with a tip about an unlikely suspect.

Stories from the streets of Hollywood, including an interview with producer Jason Blum about how he is revamping the horror genre; Jamie Lee Curtis, Jordan Peele and Octavia Spencer discuss what it is like to work with Blum.

Former actress Catherine Oxenberg shares how she tried to save her daughter from controversial self-help group NXIVM; interview with cult deprogramming expert Rick Alan Ross.

A beloved former firefighter is found dead in his garage; a neighbor's home security camera may provide answers.

When two mothers meet after one of their sons disappears after a college party, their search for answers leads them down an unexpected path.

After teenagers Rachel Shoaf and Sheila Eddy are convicted of murdering their 16-year-old friend, Skylar Neese, Skylar's parents discuss the night she disappeared; Rachel Shoaf's therapist, Patricia Bailey, shares her thoughts.

A popular high school student is found murdered in her bed; two students help police solve the case.

An in-depth look at the journalists who exposed the dangers of cult leader Reverend Jim Jones; interviews with witnesses to murders carried out by Jones' followers.

A husband convicted of murdering his wife is granted parole; others fear he may kill again.

A woman whose ex-husband killed six people in Arizona, allegedly targeting individuals with connections to their divorce; interviews with experts on the topics of domestic violence and mass murder.

The reality of life along the U.S.-Mexico border, including interviews with families seeking asylum, news on the controversial policy of separating migrant families, and fact checks on claims made by both political parties.

When a prominent attorney claims to have accidentally shot his wealthy wife, the local prosecutor questions his story.

A woman's DNA test sends her father halfway around the world to confront his past.

A father in Hawaii tackles setback after setback in his fight for justice for his murdered daughter.

A recent law school graduate in Georgia who has a promising future disappears without a trace.

Sixteen parents fighting to end college hazing at fraternities speak out together for the first time; cases of alleged hazing at various universities.

Interview with Andrea Constand, the first woman to pursue charges against Bill Cosby, and four other Cosby accusers who testified against him.

A look at the future of marijuana in the United States, including state-of-the-art science and interviews with patients, their families, leading scientists, doctors, federal legislators and a former professional football player.

In a suburb of Toronto, a family lives in fear as one relative after another is found dead over the years in the same house.

When a young woman is found dead in a field on the outskirts of Green Bay, Wis., a fitness tracker helps detectives solve the mystery.

Rapper Meek Mill interview; exploring controversies surrounding the criminal justice system, including the parole system, wrongful convictions, challenges faced by law enforcement, alleged police abuse and more.

After a 15-year-old girl disappears, investigators discover a creek where the local teenagers hang out that may hold the answer to her disappearance.

When one woman breaks off her relationship with a boyfriend she says abused and stalked her, he moves on to something even worse.

The disappearance of a young woman from Bend, Oregon leads to an intense manhunt after the suspect sets off on a two state crime spree. Keith Morrison reports.

Former gymnastics team coordinators Bela and Martha Karolyi and Olympic gold medalist McKayla Maroney talk exclusively to Savannah Guthrie about the biggest sex abuse scandal in Olympic history.

Dennis Murphy on the latest developments in a bizarre cyber-revenge case that lands a young woman in jail. Andrea Canning reports on a murdered Tennessee woman whose case stumps investigators

Four families that barely escaped the catastrophic Montecito, Calif., mudslides alive, and the rescuers who risked their own lives to help.

When a young Florida law professor is shot, baffling his family, friends and police, a complicated investigation leads police to a surprising theory of the crime; the victim's family speaks out for the first time.

Former DEA agent Andrew Hogan details his search for Mexican drug lord Joaquín "El Chapo" Guzmán.

A complicated Texas love triangle ends in murder. Apink gun leads to an arrest, until new evidence prompts investigators to rethink the case.

A woman's death is initially ruled a suicide, but when a new investigation begins, police begin to suspect murder.

A former marine who may have let his desire to help go too far.

When a young Army medic goes missing, police get help from an unorthodox private investigator.

Megyn Kelly sat down for two exclusive one-on-one interviews with President Vladimir Putin, which will be featured in the hour-long primetime special

When a young mother disappears after leaving her infant in the care of her local pastor and his wife, Florida detectives search for her for five years, uncovering a web of secrets and lies.

A murder outside Pleasantville, Iowa divides a family and forces one man to take the investigation into his own hands. Dennis Murphy reports.

The mysterious death of a young mother in Ohio and the ensuing investigation that spans years and multiple states.

A couple's anniversary celebration ends in murder during what appears to have been a home invasion, but investigators believe the suspect might be connected to the victim.

A look at the case of con man John Meehan, including interviews with his wife and her daughter, his ex-wife, law enforcement officers, and the Los Angeles Times reporter who shined a spotlight on the story.