Season two of RFDS picks up one year after Eliza (Emma Hamilton) left Broken Hill behind. Much has changed, with lives at RFDS South East progressing at a rapid rate. The determined team will face some of their most confronting challenges – in the air, on land, with each other, and within themselves – set against the outback's isolation, beauty and brutality.

Based on remarkable real-life stories and filmed on location in and around Broken Hill, RFDS tells the stories of doctors, nurses, pilots and support staff in the Royal Flying Doctor Service as they navigate emergency retrievals across some of the most inhospitable places in the country.

Returning cast include Emma Hamilton, Stephen Peacocke, Rob Collins, Justine Clarke, Ash Ricardo, Jack Scott, Sofia Nolan, Rodney Afif, Ash Hodgkinson and Thomas Weatherall. Joining the cast this year is Emma Harvie in the role of Chaya, a charismatic mental health nurse.

In Season One, a doctor escaping her past joins the Royal Flying Doctor Service on a day when a catastrophic emergency retrieval hits the team personally. Together they deal with the fallout, all while continuing their highly skilled work, fighting the clock and the elements to save people having the worst day of their lives.