The only thing more amazing than the lives they save are their own life stories. "20/20" Anchor Elizabeth Vargas sits down with doctors who have disabilities, are inspired by tragedy and practice improvised medicine, as they share their inspiring stories of resilience and survival. The special also goes behind-the-scenes on the set of "The Good Doctor" and interviews actor Freddie Highmore who stars in the show as Dr. Shaun Murphy, a surgical resident with autism and savant syndrome. Highmore discusses how he prepared for playing the role of a doctor with autism and how the public has responded to his role.

Former members of NXIVM, a professional coaching company, speak out about their experiences in the alleged secret society; NXIVM's litigation tactics against former members and critics.

Meghan Markle's engagement to Prine Harry; interviews with those who know Meghan; an in-depth look at Meghan's life, family, humanitarian work, and career.

Investigation into the 2002 murder of Christa Worthington and whether the man convicted actually committed the crime; a 2-hour special.

The special will include insider details on classic holiday films including a casting decision, Jim Carrey's torture-surviving technique training during "How the Grinch Stole Christmas"; and a visit to a Vancouver psychiatric hospital, the stand-in for Gimbal's toy department in "Elf." The hour will consider the question of whether favorites such as "Trading Places" and "Die Hard" qualify as Christmas movies; and talk to a spokesperson from Rotten Tomatoes to discuss what it takes to qualify as a Christmas classic. The history of small-screen favorites such as "A Charlie Brown Christmas" and "Rudolph the Red-Nosed Reindeer" will be featured, as well as interviews with the voice-over artists behind these favorite animated characters, and the owner of the fully restored Santa and Rudolph puppets.

Following the life of Nathaniel Newman -- who was born with a condition known as Treacher Collins.

Civil suits allege sexual assault and defamation regarding a college coach and an athlete.

When former Marine discovered teen son talking to ISIS recruiters; How ISIS uses the internet to target young Americans for recruitment; The fight against ISIS's reach on America's youth.

An investigation into the unanswered questions still remaining about the Las Vegas mass shooting; interviews with friends, neighbors, and a girlfriend of Paddock's; survivors and those coping with their new lives.

Twenty-seven years after a Florida woman was fatally shot on the doorstep of her home by an assailant in a clown costume, police arrest her husband's new wife.

Multiple women describe alleged encounters with Harvey Weinstein; Angelina Jolie, Gwyneth Paltrow claim Weinstein harassed them; What could happen next for Harvey Weinstein, his accusers.

Las Vegas country music festival underway, as shooter prepares in hotel; Woman describes moment when husband was shot while holding her; Remembering the Las Vegas shooting victims.

Brother recalls the last day he saw his sister Holly Bobo alive; Missing nursing student Holly Bobo's remains are found by ginseng hunters; Jury returns with verdict in man's trial for Holly Bobo's murder.

Authorities set up an elaborate sting operation to catch a Houston couple who were allegedly attempting to hire a hit man to kill their exes.

Archival footage and new interviews provide a look at the arrest and conviction of Scott Peterson in the murders of his wife, Laci, and their unborn son, even as Peterson awaits answers to an appeal and a legal petition from death row.

Doctors with disabilities and others share stories of resilience and survival in spite of tragedy.

A freshman at Northern Arizona University who shot four fraternity brothers outside of a party -- killing one -- claims self-defense, leaving the local community divided; interviews with the survivors and the parents of the young man who died.

A reality-TV executive receives a rare hand transplant after losing limbs due to a rare disease.

Who are the white nationalists and Antifa; White nationalists, counterprotesters face off in Pikeville, Kentucky; Violence erupts between white nationalists, counterprotestors in Charlottesville.

Molly Martens Corbett says husband was controlling, possessive; Former FBI agent, daughter charged with the murder of her husband; Molly Martens Corbett, her father head to prison for murder.

A jury finds a young woman whose boyfriend committed suicide with her encouragement guilty of involuntary manslaughter.

Footage of U.S. border officers accused of encouraging a 16-year-old to drink a dangerous liquid to prove he's not a smuggler; cases of border agents and officers being accused of abusing those crossing the border.

Friends of O.J. Simpson discuss the former professional football player and the armed robbery of memorabilia dealers that landed him in prison.

Investigation into the questions that still remain surrounding the 1997 murder of designer Gianni Versace.

An exploration of the nationwide crisis of road rage and how incidents can quickly become dangerous; traveling across the country with the Colorado State Patrol.

An international investigation into Otto Warmbier's 17-month imprisonment in North Korea, and his death, which occurred less than a week after he was brought back to the United States in a state of unresponsive wakefulness.

Exclusive interviews, photos and footage related to the Nixon Watergate scandal.

When a 16-year-old girl accuses a classmate of raping her at a party, the investigation divides the small Alabama town.

Tracking families that have been affected by severe attachment to digital devices, from the height of unmanageability to the journey toward recovery.

Computer programmer and businessman John McAfee discusses being named a person of interest in the murder of his neighbor and the resulting tumult. He also discusses what his life is like today.

A Tennessee high school teacher accused of kidnapping his 15-year-old student causes a 38-day manhunt that ends with the two being found in northern California; interviews with people close to the case.

Two years after the interview during which she announced she was transitioning to female, Caitlyn Jenner reconvenes with Diane Sawyer to talk about the realities of her life.

A Canadian woman who served time for catfishing professional basketball player Chris Andersen and a 17-year-old girl who had a social media presence discusses the reasons behind her scheme.

Two mothers hire a private investigator Sheila Wysocki to search for answers concerning the mysterious deaths of their children, Lauren Agee and Jonathan Crews.

What happened before woman was stranded in desert near Grand Canyon; Stranded student near Grand Canyon builds fire, sign to signal for help; Student stranded near Grand Canyon reunites with her rescuers

After spending 11 years in prison for allegedly murdering her mother, Noura Jackson is released and a new trial is ordered.

Charles Manson's tumultuous childhood and time in prison; What happened the night Sharon Tate was murdered by Charles Manson's followers; Where Charles Manson and his followers are today.

A 16-year-old gay teen whose mother sent him to a series of Christian-run youth camps that practice so-called "gay conversion therapy'' talks about his experience.

"20/20" takes a look back at the Emmy Award-winning series "Shark Tank" and the incredible American entrepreneurs behind $100 million in deals made over the past eight seasons.

The ex-wife of Justin Ross Harris talks about the death of their son and the ensuing court case.

Playboy model and reality TV star Anna Nicole Smith is remembered ten years after her sudden death.

A man claims his mother disappeared during an ill-fated fishing trip the two had embarked on.

A celebration of the life and legacy of legendary actress Mary Tyler Moore, from her childhood to her groundbreaking career.

20/20 Anchored by Elizabeth Vargas and David Muir Airs Two Special Hours Thursday and Friday, Featuring a Preview of the Inauguration, Exclusive Interviews With Ivanka Trump, Donald Trump Jr. and Eric and Lara Trump, and Live Coverage From Inaugural Balls.

Profiles of working individuals and families across America who are struggling to stay in the middle class; issues of dwindling job opportunities, income inequality and community solutions are explored.

Ex-members of the Church of Scientology who crusade against it; actress Leah Remini discusses her fight against the Church of Scientology and her goal of making it lose its tax exempt status.