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James investigates why his old pal Pandora the basset hound is feeling so low, Cat gets ready to rumble with the world's biggest rodent when she meets Clarence the capybara, and Cheryl helps 11-year-old Frankie the bedlington terrier who's been suffering from a nasty ear and eye infection.
James pays a visit to his old stomping ground and takes up the reins to tackle some supersized dental work on retired police horse Hank. Rory treats feisty fido Gloria, a Greek rescue dog with a sore foot, and Cheryl checks out a shy chameleon who's feeling a bit off colour.
James fixes Rosie the rabbit's injured leg, a food-loving dog who can't stomach grub visits Cheryl and Cat goes quackers over an abandoned duckling.
Cheryl operates on a dog with a broken leg, Rory treats a cat with some serious swelling on his side, and James has a visit from a litter of basset hound pups.
Cat gives a giraffe's achy leg a massage, James helps new mum Daisy the Chihuahua who's unwell and Cheryl calms the nerves of a scared Dalmatian.
Cat sorts out a dog's bulging belly button, James treats Socks the sickly snake and Rory operates on a big hound's badly swollen ear.
Rory takes a walk on the wild side with an Asian golden cat, Boo Boo the guinea pig needs help from Cheryl and Cat treats a dog with a badly swollen face.
James has an emergency on his hands when Charley the dog falls critically ill after eating mouldy food. Rory operates on Etty to find out what's stuck inside this greedy cat's guts and Cheryl 'makes space' in her diary for a gerbil called Tim Peake, who has a gammy eye.
All four vets are back in action as Cat retrieves an enormous blade of grass from a tom cat's nostril and Rory helps a timid terrier who needs a lump removing from his paw. Cheryl tries to make friends with a very prickly patient and James swots up to treat a tortoise who's refusing to hibernate.