Hooker holds himself personally to blame when a female rookie cop that he trained is seriously wounded in a confrontation with a pair of fleeing gun shop robbers. With the officer needing her leg amputated as a result of the wound, Hooker and Romano investigate the gun thieves who are selling their hauls to a back street crime baron.

On Stacy's first week of field training, Hooker assigns her to tough veteran officer Jim Corrigan, who has a low opinion of female cops after his former partner was killed while partnered with one. Meanwhile, Hooker has a personal concern in catching the culprits of a series of violent mini-mart robberies in a factory district, when his ex-wife Fran is badly wounded in a hold up and is in danger of being left blind as a result.

Sibling robbers hold Stacy, Fran and several hospital patients Including a little girl urgently needing heart surgery in exchange for their wounded father.

The hunt for a serial arsonist that is torching condemned buildings intensifies when a Private Investigator, who is an ex-cop and an old friend of Hooker's, is murdered. Certain that the man was on the verge of finding out who is behind the attacks, Hooker and Romano work with his daughter, who is also a PI, to bring the arsonist to justice.

Hooker and Romano team up with a Gamblers Anonymous counselor to bust a drug lord who blackmails compulsive gamblers into serving as drug mules.

Hooker sets out to capture the murderer of a young woman who witnessed a payoff to a city councilman.

Hooker confronts an old buddy, Lt. Paul McGuire, seeking revenge against a rapist.

While investigating armored car thefts, Hooker sympathizes with the sister of one of the suspects.

Much to Hooker's discomfort, Stacy volunteers to be a decoy when a series of murders plagues the marina area.

Romano's in love with a fashion model and deaf to Hooker's suspicions that she's a member of a ruthless ring of fur coat thieves.

The tragedy of teenage drinking hits Romano in the heart when he learns the young son of his fallen war buddy is an alcoholic supporting his habit by selling booze to his high school classmates and who is now escalating into bigger crimes.

Hooker and Romano will stop at nothing to squash a PCP operation after a schoolgirl hallucinating on angel dust tries to fly from atop her high school and a rookie cop friend of Romano's is almost killed when acting as an undercover narc.

Hooker tries to avert a war between independent truckers and a produce wholesaler who's been sabotaging their trucks.

An ambitious drug lord directs a street gang to deal high grade heroin in Hooker's beat, meanwhile setting up a hearing impaired teenage gang member to take a murder rap, but Hooker suspects the boy is innocent and vows to help him.

A detective is out to nail Hooker's friend on a charge of aiding jewel thieves while working as a security guard.

Hooker is accused of killing an unarmed youth during a shootout that put Romano in the hospital.

A vengeful sniper who has been shooting at police cars is planning to attack the police academy.

A large footprint is Hooker and Romano's only clue to a man who has been sexually assaulting women joggers.

Hooker and Romano try to protect a frightened robbery witness from the culprits — who don't know she's blind.

Romano struggles with the cold hard reality of being a cop on the street when he fails to shoot a cop killer. When the killer gets released on a bargained down technicality by lying, Hooker and Romano strive to bring him to justice.

Hooker works to clear an old racing buddy arrested in connection with thieves using loot to rebuild race cars.

The murder of a dancer who has had a lock of her hair cut off signifies to Hooker that a serial killer he pursed eight years previously is back in operation. Hooker is concerned for the only victim to survive one of the previous attacks - a dance teacher with whom he nearly fell in love - and sets about protecting her, believing that the killer will go after her again to try and finish the job.