What is life in prison really like for the fastest growing segment of incarcerated Americans? Chris Cuomo is granted unprecedented access to New York State's only maximum security prison for women, witnessing some of the most important moments of some of the inmates' lives.

More and more American children are being recruited into the sex trade, sometimes girls as young as 10 years old. Chris Cuomo explores the mean streets of Los Angeles, California, where law enforcement battles this rising tide of exploitation.

Emotionally-charged custody battles take place with increasing frequency in two small towns on the border of Arizona and Utah. Chris Cuomo finds himself in the middle of an hours-long tug of war, and meets mothers and fathers who have fought long and hard to reclaim their kids, at great personal cost.

An alarming number of bodies is piling up in Dr. Corrine Stern's jurisdiction, and it's her job to figure out who they are and why they've died. She is the lone medical examiner in the border town of Laredo, Texas and has become an expert in identifying the bodies of migrants who die crossing the border.

Addicts are found over-dosing on the streets every day in New Hampshire, the small, bucolic state President Trump recently called a drug-infested den. Chris Cuomo visits the front-lines of America's opioid epidemic to see what's being done to turn this deadly tide.