At first it looked like a home invasion gone wrong at the house Ralph Candelario shared with his second wife, but when police learn the antique dealer's first wife had disappeared, they take a closer look.

A California couple's romantic getaway on a boat turns tragic when the young wife and mother is lost at sea. Did she accidentally drown or was it something more sinister? The case goes cold for years — until a gorgeous model with a checkered past goes undercover to find the truth. Josh Mankiewicz reports.

Memphis wife and mother Heather Jones embarks on a remarkable weight loss journey, and then disappears.

The FBI gets involved when a Virginia man's wife and son are kidnapped while vacationing in the Philippines, with a terrorist group demanding millions in ransom.

A wife and a mistress vying for the same man end up in a high-speed showdown on a highway; after the man of their dreams, on his motorcycle nearby, gets struck and killed, his wife becomes accused of his murder.

A young mother disappeared one morning. Her husband said she went out for a run and never came home. She was found strangled to death. Was her husband capable of murder? What would the jury decide?

A newlywed received terrifying emails with threats of kidnapping and death. The emails appeared to come from an ex-girlfriend. But hiding behind the threats was a cyber-secret. It was a dangerous game with someone playing for keeps.

If a killer is still free after 25 years, then maybe they got away with murder; the trail goes cold, never to warm up again, until one day it does.

A popular teacher is savagely murdered in her home; there is an arrest, a trial, and a conviction, but when a bombshell comes in after the verdict, the convicted murderer is given a chance at freedom.

Big sky country and a dangerous highway set the scene of a fatal car crash; determining if the tragedy was an accident or a crime and the secrets behind the truth hiding in text messages sent just before a car crossed the line.

A woman's life ends in mystery on a dead end road; a mother of three, loved by her family and tight-knit community; for years the murder investigation went cold, but secrets have a way of eventually coming out.

A mother's disappearance from a small town in Alabama is discussed.

A couple who made a fortune in gold is headed for divorce when the wife is murdered; on tape, the husband is not at the crime scene, but police think the video holds the key to unlocking a mystery.

A double murder reveals a double life; the victims are a well-respected couple whose son plays poker for a living; his alibi is his ace in the hole, but when detectives find key evidence, they think they are holding all the cards.

After Christina, the twenty-three-year-old fashionista, goes out to a high-end shopping mall on a Friday night and vanishes, police question everyone; they know someone is lying, but not who.

A hockey player finds his wife murdered in their home; his daughter says she saw a robber, but the killer's identity turns out to be far more complicated; police have their suspects but her family members have questions of their own.

A 4-year-old girl abducted and raised by her kidnapper spends decades trying to get back home, and she finally accomplishes her goal; as it turns out, that ending was only the beginning.

At first, the fatal fire that swept through the home of a young couple looked like an accident then investigators took a closer look and what they discovered about the fire, and this couple, left them burning with suspicion.

After a young mom is found dead on the side of a country road, 40 miles from her Knoxville home, investigators scramble to figure out how she ended up there.

This part of the Lone Star State is largely sheltered from hurricanes, but, as it turned out, not from one unnatural disaster.

Melissa Lewis disappeared leaving signs of a struggle and a strange orange mist behind her. Later, her boss went missing and left behind an even bigger mess, including a missing fortune. Two crimes leaving one lingering mystery.

The case made national headlines: A toddler left in the car for seven hours while his dad was at work. Was this a heartbreaking accident? Police said it was murder. Could any parent ever do this on purpose?

Stranger than fiction, a mom suddenly vanished. A dad under suspicion. There was no body, no weapon, no eyewitness and surprises along the way. Now, after all the twists and turns of four murder trials, the final verdict is in.