Derrick helps out a dog named Rex who was born without his two front legs and needs a custom cart. Then he heads to Fort Worth, Texas to meet Penny who lost a leg in a traumatic car accident and without Derrick's help may become paralyzed.

Derrick and Henry travel to Texas to help neighbors Monica and Robert with a cow and a dog, both named Penelope. Penelope the cow needs a boot to graze freely, while Penelope the dog has severe nerve damage and can't control her back legs.