Derrick and his wife, Kelly, travel to Thailand to visit Elephant Nature Park to help Mae Mai, an elephant with a painful dislocated knee. Derrick also helps a young bull elephant named Khun Dej and a bull named Mr. Cow.

Derrick helps a big dog named Bently with his back leg issues; Derrick then heads to Florida to help Ujwala and her foster dog Kala. Kala is a rescue from the streets of India who must learn to trust Derrick and the new prothesis.

Derrick travels to Sheridan, Illinois to help a camel named Moe. Due to his collapsed legs, Moe has been confined to his stall for four years and unable to go outside. For the first time, Derrick builds a set of braces for a 1500 pound camel.

Derrick helps a pup named Rosie who is missing a paw and needs a custom prosthetic. Then, Derrick travels to Los Angeles to meet a chihuahua named Roo, who was born with two legs and needs a custom cart to help her keep up with her best friend, Chase

Derrick visits California to help a sheep named Timmy and his goat friend, Poppy. Timmy and Poppy share a stall and also share front leg mobility issues.

In Lancaster, Pennsylvania, Derrick meets the Hicks family and builds a custom prosthesis for their dog, Millie, who was born with a front limb deformity.

Derrick gives a dog named Watson the chance to walk with a full limb prosthesis. Derrick then heads to Connecticut to help Peaches the goat with a custom cart.

Derrick visits a family in New Jersey to help two rescues: Angus, a cat with multiple amputations; and Lux, a dog who lost his front leg. Derrick's devices will help Lux and Angus keep up with their family.

Derrick travels to Glendale, Kentucky to help out a cuddly raccoon named Boone, who needs a custom cart so he can freely move around his home at an animal sanctuary.

Derrick heads to Colorado to build a custom prosthetic for Wesley, a two-year-old rescue dog born with a front limb deformity. Derrick hopes a new leg will help Wesley keep up with his adventurous family for years to come.