Karen has gotten so out of control with her eating that she's developed a fear of leaving the house and interacting with the world at her size. She needs Dr. Now's help, but can Karen ever qualify for weight loss surgery if she won't leave the house? 

At 6'3" and over 700 pounds, Jacky has barely had a chance to live. She's never fit in anywhere and has always felt out of place. Now that her parents have passed, she has a fresh chance to discover the world anew, but first she's got 500 pounds to lose.