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Liz, completely bed-bound, has severe lymphedema that makes it impossible to walk; utterly isolated, Liz has no friends, battles depression and lives with a mother too ill to take care of her.
Alicia, all smiles and laughter on the outside, secretly fears that her food addiction will kill her before she can marry her long-time love or watch her nieces grow up.
Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.