Dr. K's day kicks off with an emergency when a bleeding cockatiel comes into the clinic. Dr. Thielen sees three animals in one appointment including a skunk that needs to be spayed and two panther chameleons in for a wellness check. Then Dr. K finds a litany of ailments in a 9-year-old ferret and must manage its care and quality of life. Meanwhile, a quaker parakeet's owners are concerned about a tumor, only to find out that the bird is so obese that it must lose a third of its body weight and see a heart specialist. Dr. Thielen tries to relieve a gerbil of an abscess, while Dr. K cleans a mouth wound on a boa constrictor so unpleasant it affects the entire clinic.

It is sink or swim as Dr. K tries to solve mobility issues for two goldfish. A severe macaw is brought in with a serious bite wound to the foot, caused by a bigger bird. A rabbit presents with a large amount of fluid in the abdomen and the exploratory surgery reveals a shocking result. Dr. K treats a tiny yellow-bellied slider that may have pneumonia, while Dr. Thielen treats a ferret with a large tumor on her tail.