Troy and Pickle hunt a giant python known as the Night Serpent. Tess convinces Bill to try out new hunting grounds, but Bill is not sure it's a good idea. Zak and Aaron explore a notorious corner of the Everglades, and Dusty Crum has an idea to lighten his load.

Troy and Pickle face a familiar foe, while Bill and Tes defend a friend's camp from a slithering invasion. Zak and Aaron's hunt leaves a bad taste in their mouths, and Dusty Crum has a plan to work smarter not harder.