During her second year of weight-loss, Zsalynn is torn between fighting her weight and fighting for her marriage. Christina lets go of the negative influences in her life and is finally able to live the life of a twenty-something.

Away from Dr. Nowzaradan's care, Penny has returned to Maryland believing she can make the choices to lose weight, but has she truly changed? Dating for the first time in her life, Tara continues to lose weight and is learning to balance new roles.