At the close of the 19th century, Paul Reisner is one of an elite group of young doctors working on the cutting edge of medical research, under the leadership of Professor Mandry. Paul shows every sign of a brilliant career, and falls in love with Clara, a laboratory assistant. But his world is shattered when he makes a startling discovery about the professor.

Rosie Williams is haunted by the murder ofherhusband 12years previously. Herteenage son John is heading for a life of delinquency fuelled by revenge. Then, he meets Billy McVea , who runs a boxing gym, affecting all their lives

Paul, an underworld hitman, recruits his childhood friend AD on his next job - the execution of a corrupt lawyer involved in drug dealing. But the hit goes wrong.