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Cybersix, an artificial humanoid with super strength, escapes her evil creator, Professor Von Reichter. She arrives in the city of Meridiana while disguising herself as school teacher Adrian. While saving the city from Reichter's creations, Cybersix defeats monsters called "Fixed Ideas"and drinks "sustenance", in order to survive.
A giant creature appears on the offshore and it heads towards the city of Meridiana. Jose finds out what the Monster is and attempts a revolt against his father.
Grizelda, a woman with the ability to become invisible, comes to Cybersix and attacks her persistently.
Jose captures Data 7 and tries to decoy Cybersix to his circus show of giant mechanical creatures using Data 7 as a bait. Knowing it is a trap, Cybersix goes to rescue her friend.
One night, Cybersix saves Lucas, who has been attacked by a werewolf. The werewolf slashed across Lucas' shoulder during this fight.
An artificial Eye appears to Meridiana and it hypnotizes the people one after another. Those who saw this eye stand lifelessly on the streets with blank expressions on their faces.
One night, the Winged Goblins streak in to Meridiana City. They irrupt into a subway and cause panic within the passengers.
A police officer, Enrique, is a good friend of Julian. Julian too takes a special liking to him, and tells him about the encounter with Cybersix.
Meridiana city is filled with the countless blue birds, which begin to attack people in the city.
Lori, a female student at Meridiana High School is in love with Adrian. However, she sees Cybersix and assumes that she is having a relationship with Adrian.
Jose visits a competent private detective, Yashimoto, to ask him to conduct an investigation on Cybersix.
Von Reichter creates Terra from mud. Terra is given the special power to absorb people's abilities by simply touching them.
Von Reichter, a mad scientist who created Cybersix, sends his "bioroid" pet to Meridiana city in order to terminate Cybersix. The bioroid pet is a black panther called "Data 7".
One sleepless night, as Lucas Amato, a biology teacher at Meridiana High School, was walking down the streets, he witnesses a big man vanish into the air.