After 7-year-old Kyron Horman's stepmother drops him off at a school science fair and takes a picture, the little boy is never seen again; his disappearance is one of the largest mysteries and investigations in Oregon's history.

Infant Lisa Irwin was abducted from her crib in her family's Kansas, MO home in 2011. Her disappearance was discovered by her father Jeremy in the early morning of October 4, after coming home from his late-night job. Several cellphones are also missing from the house.