Infant Lisa Irwin was abducted from her crib in her family's Kansas, MO home in 2011. Her disappearance was discovered by her father Jeremy in the early morning of October 4, after coming home from his late-night job. Several cellphones are also missing from the house.

17-year-old Brittanee Drexel suddenly disappears from spring break in Myrtle Beach. She leaves a friend's hotel and is never seen again. But the case comes alive when twisted and disturbing details start to emerge from a prison cell.