While navigating the fallout from Katie's secret, Amy treats a critically ill patient with a dark one of her own. As Gina and Jake evaluate a world-class poker player, searching for the source of what may be a mental disorder, Jake is forced to hide the truth from Amy about Rachel's health scare. Sonya and TJ investigate their theory behind Joan's frequent absences. And Richard returns with a trick up his sleeve.

After a tragic accident, one of Joan's oldest friends is rushed to Minneapolis to be treated by her, forcing Amy to confront her about her illness. Richard and TJ find themselves at odds when they treat a tech bro who thrives on pushing boundaries. Michael tries to pick up the pieces in the wake of his fractured marriage.