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Dr. Oh sucks Matt and Zack into a video game so they can discover what it takes to defeat aging and never die. From health-bar draining breakup texts to immortal animals to rich men stealing testicles, it's a wild quest for the cheat code to live forever.
Dr. Oh is furious that Matt and Zack are watching a TV show about how aliens helped ancient Egyptians, so he takes them back 3000 years to show them how impressive the Egyptians truly were - no aliens required. They also find out what "ithyphallic" means.
Dr. Oh logs Matt and Zack on to the Tree Internet where trees use fungus to communicate, share resources and live in harmony… or do they!? Matt and Zack hack into the root system and learn this underworld is far seedier than they could ever imagine.
Zack finds out he's part Neanderthal, so he and Matt spark up Dr. Oh to trip back to when six different species of humans all walked the Earth at the same time! It's a human family reunion that reveals why Homo Sapiens are the only ones still partying.
With NASA's Artemis moon missions on the horizon, Dr. Oh blasts Matt and Zack into space to replay the moon's wild birth, crash a rocket into the moon to find some ice, and discover the moon's secret treasures above ground...and below.