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Fitz and Chen are put into isolation, after Fitz returns home with a mysterious ailment. Ming undergoes quarantine at home, where she reconsiders their adoption plan.
While en route to medevac a patient in Guatemala, Fitz recalls the events that occurred after Christmas eve. At Mercy, Ming tends to a pregnant patient, but the situation quickly turns into an emergency.
Ming finally sees her dream of being a mother come true, though the donor plans she and Chen made with Fitz undergoes some changes. Through this, Fitz learns how to love and be loved, and Chen feels confident to pursue a writing career.