In 2009, a routine Air France Flight 447 goes missing over the Atlantic Ocean. Investigators discover this tragedy could happen again.

In 1908, a huge area of Siberian forest is devastated. But whatever caused the damage has completely vanished. This is the Tunguska event and new evidence may solve this century-old mystery.

After five planes vanish in the Bermuda Triangle, new science suggests a strange geological force is responsible; satellites reveal lost tribes living in the Amazon jungle, but some civilizations remain missing, stumping experts.

In 2013, a Florida man is in bed when his room is swallowed by the Earth. Experts wonder if a rare and unpredictable kind of sinkhole is to blame.

The Roanoke colony vanishes without a trace from Roanoke Island, North Carolina. Centuries later, it remains one of history's greatest unsolved mysteries; but new evidence may, at last, reveal its fate.

New technology reveals lost cities in inhospitable jungle and researchers wonder if the mythical city of El Dorado could be the next discovery. After a crystal is found on a shipwreck, experts believe it could prove how Vikings discovered America.

In 1962 three convicts attempt the impossible; a prison break from Alcatraz. The official line is that the men drowned, but a new scientific experiment suggests they made it to the shore. Secret FBI reports hint they could have fled to Brazil.

A huge cargo ship suddenly vanishes with 27 crew members on board; new evidence suggests the culprit may be a mythical rogue wave. Recently discovered evidence could prove the existence of a ghost ship in the California desert.

Atlantis is one of the most famous disappearances of all time. After thousands of years, state-of-the-art technology might finally be able to crack this ancient mystery. And after nine hikers die in a gruesome cold case, new science provides a hot lead.

The first episode chronicles the biggest aviation mystery of the 21st century, Malaysia Airlines Flight MH370 in 2014, and attempts to determine how something so closely monitored could simply vanish. Rescue crews search its last known position but find nothing. The fate of the flight remains a mystery; theories abound but facts are few.