Michael, Lincoln and Kellerman takes the airwaves hostage as they attempt to evade the authorities and get a message to a missing Sara; Bellick gets a surprise visit in Fox River's infirmary; Haywire resurfaces and lands in more trouble; Sucre takes his good Samaritan for a ride.

Michael and Sara realize that Warden Pope (guest star Stacy Keach) is the key to recovering information that will bring down 'The Company'; Mahone corners another escapee; C-Note fears for his daughter's life; Sucre learns the dangers of hitchhiking en route to reuniting with Maricruz; and T-Bag walks down memory lane when he takes the Hollander family to his childhood home.