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When Sara and her son's safety is threatened, Michael and Lincoln recruit the help of Sheba and C-Note to try and catch Poseidon. Meanwhile, Whip goes on a separate mission and T-Bag reveals a secret.
Sara becomes fearful of her family's safety when she discovers the real reason that Michael faked his own death. In the meantime, Michael and Lincoln continue to try find a way home with the help of Sucre, and the real identity of Poseidon is revealed.
Dangerous threats keep Michael and Lincoln fighting to protect Sara and Mike. Meanwhile, Poseidon continues to try and outsmart Michael and the rest of the gang, which leads them to the ultimate showdown, and not everyone makes it out alive.
In the next action-packed chapter of PRISON BREAK, original series stars Wentworth Miller, Dominic Purcell, Sarah Wayne Callies, Amaury Nolasco, Robert Knepper, Rockmond Dunbar and Paul Adelstein are reunited for an all-new adventure spanning the globe. When clues surface that suggest a previously thought-to-be-dead MICHAEL SCOFIELD (Miller, "The Loft") may be alive, his brother, LINCOLN BURROWS (Purcell, "DC's Legends of Tomorrow"), reunites with Michael's wife, SARA (Callies, "Colony," "The Walking Dead"), and Fox River State Penitentiary's most notorious escapees to engineer the series' biggest breakout ever.