MacGyver is on his way out of Bulgaria with a secret microfilm, when he meets Penny Parker, a beautiful, talkative American, who is on the run from her lover, a man named Stephan Frolov. She stashes some jewels on MacGyver, thus making him a suspect, and now MacGyver and Penny must flee Bulgaria together.

A 15-year-old genius accidentally hacks into a defective missile guidance system and attracts the attention of both the FBI and some black marketeers, who think that she may fix it for them. It's up to MacGyver to save her from being kidnapped by either side.