In Afghanistan, wounded and hunted by the Soviets, MacGyver is given refuge by an Afghan woman and her son. But they are themselves at the mercy of an Afghan thug, who will kill MacGyver if he finds him at his woman.

MacGyver is somewhere in Asia to retrieve documents for his government. Soon after, a local tribe stops the train. They take all passengers hostage until the men responsible for the death of the tribal leader's son is found among the passengers.