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Love blossoms between Carl Sagan and Ann Druyan; Russian cosmonauts make the first spacewalk; Wernher von Braun becomes a pioneer in rocket science.
J.T. McWilliams forms a community but is muscled out by William Clark; Bugsy Siegel bets his life on the Flamingo Casino; the Moulin Rouge is the first casino to break the color barrier.
Alexander Graham Bell steals the original design for the telephone from Elisha Gray, and Thomas Edison tries to create a movie-making monopoly.
The Pueblo Indians revolt against the Spanish, Boy Scout founder Ernest Thompson Seton hunts a wolf, and a mysterious crash in Roswell appears to be alien debris.
Vigilantes led by Andres Pico enact street justice; Rin Tin Tin becomes the world's biggest movie star; the construction of the Los Angeles aqueduct brings makes city officials rich.
Nellie Bly and Elizabeth Bisland try to travel around the world in under 80 days, and Thomas Nast's political cartoons lead to the downfall of Tammany Hall leader "Boss" Tweed.
A land claim in Oklahoma is made by Kentucky Daisy; astronaut Gordon Cooper goes on a space mission; Deputy U.S. Marshal Bass Reeves becomes the inspiration for the Lone Ranger.
Board games become popular thanks to Milton Bradley; a pinball ban is overturned with help from Roger Sharpe; Bobby Fischer beats Boris Spassky at chess during the Cold War.
Wayne Wheeler leads the Prohibition charge, Dorothy Fuldheim paves the way for women in journalism, and Muhammad Ali refuses to fight in the Vietnam War.
Harriet Tubman provides military intel to the Union Army, Virginia Hall spies in France during World War II and becomes the first woman in the CIA, and Roald Dahl serves as a debonair British spy. Featuring Octavia Spencer, Alia Shawkat and Will Ferrell.
Pirate John Lafitte helps Andrew Jackson defeat the British during the War of 1812, Sam Zemurray becomes a banana kingpin, and Louis Armstrong becomes a jazz legend. Featuring Jack McBrayer, Thomas Middleditch, Jason Momoa, Miles Brown and Andre Royo.
Actor Clark Gable joins the Air Force during World War II, Ponce de Leon quarrels with Diego Columbus, and Griselda Blanco takes over the cocaine trade in Miami. Featuring Josh Hartnett, Maya Rudolph, David Koechner and Johnny Knoxville.
Paleontologists Othniel Marsh and Edward Cope become rivals, and Penzias & Wilson discover the echo of the Big Bang. Featuring Greg Kinnear, Stephen Merchant, Justin Long, Jason Ritter, Tony Hale and Christopher Meloni.