Harold likes to gamble, but as a rule he loses and he is heavily in debt. His uncle is the famous Big Fred who is the owner of a football team and he is a millionaire. But Harold can't get a dime from him. So Harold decides to kill his uncle by a pipe bomb under his car. He is not surprised when he is told Big Fred is dead. He is surprised however that the death is due to a road accident. He rushes to his uncle's house and he finds Lt. Columbo getting excited about the car with the bomb...

Columbo attends his nephew's wedding and as the couple get ready to leave on their honeymoon, the bride disappears; Columbo investigates and suspects his nephew may have made a few enemies on the police force.