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Monk's hundredth case, involving a serial killer, is covered by a TV news magazine, but while watching it he realizes that a second unknown killer was responsible for one of the murders.
Monk is smitten with an attractive former dancer and when she's accused of murder, he agrees to help her, even though all the evidence points to her, and continues searching... even after she confesses to the crime.
Monk's hypnotic regression to his childhood begins to affect the case on which he's consulting - an actress who's disappeared, and the holes in her story when she's found after a deadly escape.