With the demise of their beloved father and Karai incapacitated, the Turtles, April, and Casey infiltrate Super Shredder's new lair to put an end to Oroku Saki once and for all, no matter what it takes.

Splinter must lead the turtles and the Mighty Mutanimals on the hunt to defeat his old enemy.

A dangerous female mutant by the name of Alopex appears with a personal vendetta against Tiger Claw.

Raphael's bonding with little Chompy gets interrupted by the invasion of Tokka, who has come to Earth searching for him.

Donatello becomes concerned and decides to test April, only to discover that her psychic abilities are rapidly growing in power.

The Turtle team hunts for their Sensei, but soon realizes they are being hunted as well.

For the first time, the Turtles encounter something they cannot defeat – the Super Shredder!

Michelangelo befriends some odd, new superheroes named Wingnut and Screwloose.

Don Vizioso's gang tracks the Turtles with a slew of Anti-Mutant weapons.

Raphael must overcome his fear of insects to lead the team when they are forced to battle Stockman-Fly's new insect minions.

When Leonardo secretly allies himself with Karai, he gets himself into deeper danger than he could have realized.

April faces a deadly new enemy when she graduates to full Kunoichi; the Turtles must deal with the return of some old foes.

As the team finally reaches Earth, Fugitoid reveals a horrible secret about his past.

The team must overcome impossible odds in order to obtain the final Black Hole Generator piece that is located on the planet Magdomar.

When Raphael loses his fighting mojo, he must overcome his feelings to save his brothers from certain doom.

Donatello is feeling inferior to Fugitoid, but his intellect is put to the test when the Triceratons attack.

The Turtles are transported to another dimension where they meet their 1980s counterparts and work together to battle Krang.

The Turtles journey through an ocean-like area of space.

The Turtles must gain the trust of the Utrom Council in order to find the next piece of the black hole generator.

The Turtles are captured by the Triceratons and are forced to fight in a gladiator-like arena for their lives.

When microscopic aliens invade Mikey's mind, the Turtles have to chase them through the strange world of Mikey's subconscious.

The Turtles find themselves on a planet of pure evil.

A shark-like bounty hunter is hired by Lord Dregg to destroy the turtles, who choose to hide out in an abandoned space station.

Casey releases a wish-granting alien named Wyrm, who wants his freedom to do whatever he wants to the universe.

When the Team crash lands on an ice moon along with the enemy, they must put their differences aside to survive.

The Team meets a strange alien robot called the Fugitoid.