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The team take the dying Abigail to the plane so that Abe, Mitch, and Max can save her life... unaware that Jamie has offered Duncan his life if he kills Abigail. Meanwhile, Dariela takes a new job and Abe tries to save Clem.
With the aid of a captive Shepherd, Jamie and the others trace Mitch--now Mr. Duncan--to Copenhagen. Meanwhile, Jackson escapes his captivity and goes after Abigail, while Logan finds a hybrid nest in Seoul.
Clem manages to revive the team, but they're trapped on the airstrip in Seoul amidst a cloud of spores. As they struggle to survive, Clem goes into labor and one team member will have to make the ultimate sacrifice to save the others.
In season three, the year is 2027 and the world has reached a tipping point: as the human population continues to dwindle due to the sterility problem, an equally devastating threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures, hell-bent on destroying Mankind.