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In season three, the year is 2027 and the world has reached a tipping point: as the human population continues to dwindle due to the sterility problem, an equally devastating threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures, hell-bent on destroying Mankind.
Mitch figures out a way to shut down most of the beacons, and have Jackson shut down the last one. However, it may cost Jackson his life. Meanwhile, the hybrids invade the barrier complex, and Logan takes Clem and the baby to safety.
Abigail brings the jet down as part of her scheme to get revenge on Jackson because she believes that he killed their father. Meanwhile, Dariela and Tessa lead a tac team to the jet to rescue their friends.
Clem manages to revive the team, but they're trapped on the airstrip in Seoul amidst a cloud of spores. As they struggle to survive, Clem goes into labor and one team member will have to make the ultimate sacrifice to save the others.
The team take the dying Abigail to the plane so that Abe, Mitch, and Max can save her life... unaware that Jamie has offered Duncan his life if he kills Abigail. Meanwhile, Dariela takes a new job and Abe tries to save Clem.
With the aid of a captive Shepherd, Jamie and the others trace Mitch--now Mr. Duncan--to Copenhagen. Meanwhile, Jackson escapes his captivity and goes after Abigail, while Logan finds a hybrid nest in Seoul.
While Logan tries to determine how the Black Forest hikers died, the jet suffers a series of malfunctions. Meanwhile, Abigail taunts Jackson in an attempt to get him to use his animal control powers and provide her with the missing piece of the puzzle.
After rescuing Isaac and the other children, the team travels to Peru to find the first of the three remaining hybrids and meet a familiar face. Meanwhile, Abe and Dariela try to work out their marital difficulties, and complications arise with Clem's baby.
Mitch rescues Clementine, while Abe discovers that a combination of the baby's DNA and the hybrids' spinal fluid could provide a cure to the TX sterility. Meanwhile, Jamie and Logan learn about Abigail's mysterious partner, Mr. Duncan, and try to identify him.
Jamie asks Mitch to represent her as her lawyer in the murder case against her. Meanwhile, Jackson meets up with Tessa again, and Dariela finally tells Abe that she arranged for Clementine's abduction in return for their son's freedom.
The team reunites to stop Abigail from leading the hybrids to the East Coast... and the rest of the world. Meanwhile, Jamie gets a lead on the Falcon, and Abe and Dariela disagree on how to rescue Isaac.
Mitch deals with the news about how Clementine was raised while he was in the tank. Meanwhile, Jackson tells Tessa who he is, and Leanne negotiates with Abe and Daniela for the return of their son.
Abe and Daniela discover that the embryo is sending a signal summoning the hybrids, and they've been chosen as part of a special Reiden project. Meanwhile, the soldiers question Mitch about Project Blue Diaspora, and Logan pays Jackson a visit.
It's ten years since Mitch died and the sterility gas was unleashed. Abe, now a doctor, is trying to find a cure. Meanwhile, Jackson and his new girlfriend Tessa rescue refugees in Portland, Logan is a NYPD detective, and Jamie is trying to track down the Shepherd's leader before he unleashes a greater cataclysm. Meanwhile, an IADG team finds Mitch in an abandoned Russian lab.
In season three, the year is 2027 and the world has reached a tipping point: as the human population continues to dwindle due to the sterility problem, an equally devastating threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures, hell-bent on destroying Mankind.
The danger escalates as the animal mutation moves to Phase 2, and they begin attacking infrastructure and creating deadly environmental phenomena in a bid to make the planet uninhabitable. Also, the team discovers a mutation that threatens the life of one of their own.
Zoo is a global thriller about a wave of violent animal attacks against humans sweeping the planet. Jackson Oz is a young, renegade American zoologist who spends his days running safaris in the wilds of Africa when he begins noticing the strange behavior of the animals. As the assaults become more cunning, coordinated and ferocious, he is thrust into the race to unlock the mystery of the pandemic before there's no place left for people to hide.