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The team reunites to stop Abigail from leading the hybrids to the East Coast... and the rest of the world. Meanwhile, Jamie gets a lead on the Falcon, and Abe and Dariela disagree on how to rescue Isaac.
Mitch deals with the news about how Clementine was raised while he was in the tank. Meanwhile, Jackson tells Tessa who he is, and Leanne negotiates with Abe and Daniela for the return of their son.
Jamie asks Mitch to represent her as her lawyer in the murder case against her. Meanwhile, Jackson meets up with Tessa again, and Dariela finally tells Abe that she arranged for Clementine's abduction in return for their son's freedom.
In season three, the year is 2027 and the world has reached a tipping point: as the human population continues to dwindle due to the sterility problem, an equally devastating threat rises in the form of "the hybrids," an army of unstoppable lab-made creatures, hell-bent on destroying Mankind.